发明授权
- 专利标题： Alpha-fetoprotein Immu31 antibodies and fusion proteins and methods of use thereof
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申请号： US13090391申请日： 2011-04-20
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公开(公告)号： US08084029B2公开(公告)日： 2011-12-27
- 发明人: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- 申请人： Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- 申请人地址： US NJ Morris Plains
- 专利权人： Immunomedics, Inc.
- 当前专利权人： Immunomedics, Inc.
- 当前专利权人地址： US NJ Morris Plains
- 代理商 Richard A. Nakashima
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
The present invention provides humanized, chimeric and human anti-alpha-fetoprotein antibodies, fusion proteins, and fragments thereof. The antibodies, fusion proteins, and fragments thereof, as well as combinations with other suitable antibodies, are useful for the treatment and diagnosis of hepatocellular carcinoma, hepatoblastoma, germ cell tumors carcinoma and other AFP-producing tumors.
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