发明授权
- 专利标题: Regulated apoptosis
- 专利标题(中): 调节凋亡
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申请号: US12684064申请日: 2010-01-07
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公开(公告)号: US08084596B2公开(公告)日: 2011-12-27
- 发明人: Gerald R. Crabtree , Peter Belshaw , Stuart L. Schreiber , David M. Spencer , Thomas J. Wandless
- 申请人: Gerald R. Crabtree , Peter Belshaw , Stuart L. Schreiber , David M. Spencer , Thomas J. Wandless
- 申请人地址: US CA Stanford US MA Cambridge
- 专利权人: The Board of Trustees of the Leland Stanford Junior University,President and Fellows of Harvard College
- 当前专利权人: The Board of Trustees of the Leland Stanford Junior University,President and Fellows of Harvard College
- 当前专利权人地址: US CA Stanford US MA Cambridge
- 代理机构: Ropes & Gray LLP
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C12N15/63 ; C12N15/85
摘要:
We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
公开/授权文献
- US20100323420A1 REGULATED APOPTOSIS 公开/授权日:2010-12-23
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