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Invention Grant
US08088728B2 Airway administration of tissue factor pathway inhibitor in inflammatory conditions affecting the respiratory tract 有权
组织因子途径抑制剂在影响呼吸道炎症反应中的气道给药

  • Patent Title: Airway administration of tissue factor pathway inhibitor in inflammatory conditions affecting the respiratory tract
  • Patent Title (中): 组织因子途径抑制剂在影响呼吸道炎症反应中的气道给药
  • Application No.: US11993253
    Application Date: 2006-06-23
  • Publication No.: US08088728B2
    Publication Date: 2012-01-03
  • Inventor: Lars Otto Uttenthal
  • Applicant: Lars Otto Uttenthal
  • Applicant Address: DK Horsholm
  • Assignee: Drugrecure APS
  • Current Assignee: Drugrecure APS
  • Current Assignee Address: DK Horsholm
  • Agency: Licata & Tyrrell P.C.
  • International Application: PCT/IB2006/002602 WO 20060623
  • International Announcement: WO2006/136962 WO 20061228
  • Main IPC: C07K14/00
  • IPC: C07K14/00 ;  A61K38/00
Airway administration of tissue factor pathway inhibitor in inflammatory conditions affecting the respiratory tract
Abstract:
The present invention provides methods for the local treatment of acute and chronic extravascular pulmonary fibrin deposition and/or reducing unwanted effects associated with systemic administration of natural anticoagulants to a subject via airway administration to the subject by intratracheal, intrabronchial or intraalveolar routes of natural anticoagulants or biologically active derivatives thereof.
Abstract(Chinese):

本发明提供了用于局部治疗急性和慢性血管外纤维蛋白沉积的方法和/或减少与天然抗凝血剂全身给药至受试者相关的不需要的影响，所述方法是通过气管内给予受试者的经气管内，支气管内或肺内途径的天然抗凝剂或 其生物活性衍生物。

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