Invention Grant
US08088792B2 Triazolopyridinone derivatives for use as stearoyl CoA desaturase inhibitors
失效
用作硬脂酰CoA去饱和酶抑制剂的三唑并吡啶酮衍生物
- Patent Title: Triazolopyridinone derivatives for use as stearoyl CoA desaturase inhibitors
- Patent Title (中): 用作硬脂酰CoA去饱和酶抑制剂的三唑并吡啶酮衍生物
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Application No.: US12417891Application Date: 2009-04-03
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Publication No.: US08088792B2Publication Date: 2012-01-03
- Inventor: Dmitry Koltun , Jeff Zablocki
- Applicant: Dmitry Koltun , Jeff Zablocki
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Agent J. Elin Hartrum
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D471/02 ; C07D491/02 ; C07D498/02
Abstract:
The present invention discloses triazolopyridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
Public/Granted literature
- US20090253738A1 TRIAZOLOPYRIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS Public/Granted day:2009-10-08
Information query
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