A mechanism that enables an optical transceiver to configure memory on a per-segment basis. The optical transceiver includes a processing entity, system memory and a memory configuration table. The memory configuration table is comprised of configuration entries, each of which defines the configuration setting for a corresponding segment of memory. The processing entity reads the configuration entries for a particular segment of the memory. The processing entity then determines the set of one or more configuration settings for the memory segment based on the configuration entry read. This process may be repeated for multiple segments of memory.