发明授权
US08093264B2 Fused heterocycles as inhibitors of VEGF receptor and HGF receptor signaling
有权
融合杂环作为VEGF受体和HGF受体信号传导的抑制剂
- 专利标题: Fused heterocycles as inhibitors of VEGF receptor and HGF receptor signaling
- 专利标题(中): 融合杂环作为VEGF受体和HGF受体信号传导的抑制剂
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申请号: US11438133申请日: 2006-05-19
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公开(公告)号: US08093264B2公开(公告)日: 2012-01-10
- 发明人: Oscar Mario Saavedra , Stephen William Claridge , Lijie Zhan , Franck Raeppel , Arkadii Vaisburg , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Ljubomir Isakovic , Marie-Claude Granger , Naomy Bernstein
- 申请人: Oscar Mario Saavedra , Stephen William Claridge , Lijie Zhan , Franck Raeppel , Arkadii Vaisburg , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Ljubomir Isakovic , Marie-Claude Granger , Naomy Bernstein
- 申请人地址: CA St. Laurent, Quebec
- 专利权人: Methylgene Inc.
- 当前专利权人: Methylgene Inc.
- 当前专利权人地址: CA St. Laurent, Quebec
- 代理机构: Wood, Phillips, Katz, Clark & Mortimer
- 主分类号: A01N43/42
- IPC分类号: A01N43/42
摘要:
The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds of general formula (A) wherein A1 is sulfur, A3 is CH, A2 is CH, D is heterocycle, Z is oxygen, SO0-2 or NR, Ar is phenyl and G is not a ring, and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
公开/授权文献
- US20070004675A1 Inhibitors of VEGF receptor and HGF receptor signaling 公开/授权日:2007-01-04
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