发明授权
- 专利标题： Soluble IL-17RCx4 and fusion proteins thereof
- 专利标题（中）： 可溶性IL-17RCx4及其融合蛋白
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申请号： US12580112申请日： 2009-10-15
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公开(公告)号： US08093355B2公开(公告)日： 2012-01-10
- 发明人: Rolf E. Kuestner , Zeren Gao , Steven D. Levin , Mark W. Rixon
- 申请人： Rolf E. Kuestner , Zeren Gao , Steven D. Levin , Mark W. Rixon
- 申请人地址： US WA Seattle
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： US WA Seattle
- 代理机构： Nelson Mullins Riley & Scarborough LLP
- 代理商 Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- 主分类号： C07K1/00
- IPC分类号： C07K1/00 ; C07K14/00 ; C07K17/00
摘要：
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. IL-17RC is a common receptor for IL-17A and IL-17F. The present invention includes methods of using a soluble IL-17RC receptor, IL-17RCx4 for treating inflammation.
公开/授权文献
- US20100113748A1 SOLUBLE IL-17RCX4 AND METHODS OF USING IN INFLAMMATION 公开/授权日：2010-05-06