Methods, systems and computer program products for compensating repeatable run-out (RRO) are described. In some implementations, RRO may be compensated by predicting the RRO and subsequently subtracting the predicted RRO from the actual value of the RRO to cancel out the undesired effect caused by the RRO during operation. More specifically, RRO generated at each spindle motor rotation may be predicted by measuring the position errors associated with the RRO with respect to a current position of a read/write head. A computational model then may be utilized to determine one or more correction factors to compensate for the RRO.