Invention Grant
- Patent Title: Diazaquinolones that inhibit prolyl hydroxylase activity
- Patent Title (中): 抑制脯氨酰羟化酶活性的二氮喹诺酮类
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Application No.: US12150998Application Date: 2008-05-02
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Publication No.: US08097620B2Publication Date: 2012-01-17
- Inventor: Jennifer R. Allen , Kaustav Biswas , Roland Burli , Jennifer E. Golden , Stephanie Mercede , Christopher M. Tegley
- Applicant: Jennifer R. Allen , Kaustav Biswas , Roland Burli , Jennifer E. Golden , Stephanie Mercede , Christopher M. Tegley
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D413/14 ; A61K31/519 ; A61K31/5355 ; A61P3/10 ; A61P35/00 ; A61P29/00
Abstract:
Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
Public/Granted literature
- US20090099171A1 Diazaquinolones that inhibit prolyl hydroxylase activity Public/Granted day:2009-04-16
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