发明授权
US08101181B2 Antibodies that immunospecifically bind to B lymphocyte stimulator protein
有权
免疫特异性结合B淋巴细胞刺激蛋白的抗体
- 专利标题： Antibodies that immunospecifically bind to B lymphocyte stimulator protein
- 专利标题（中）： 免疫特异性结合B淋巴细胞刺激蛋白的抗体
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申请号： US12552915申请日： 2009-09-02
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公开(公告)号： US08101181B2公开(公告)日： 2012-01-24
- 发明人: Steven M. Ruben , Gil H. Choi , Tristan Vaughan , David Hilbert
- 申请人： Steven M. Ruben , Gil H. Choi , Tristan Vaughan , David Hilbert
- 申请人地址： US MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： US MD Rockville
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.