发明授权
- 专利标题： Tuberculosis vaccines comprising antigens expressed during the latent infection phase
- 专利标题（中）： 包含在潜伏感染期间表达的抗原的结核病疫苗
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申请号： US13101980申请日： 2011-05-05
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公开(公告)号： US08101193B2公开(公告)日： 2012-01-24
- 发明人: Claus Aagaard , Carina Vingsbo-Lundberg , Peter Andersen
- 申请人： Claus Aagaard , Carina Vingsbo-Lundberg , Peter Andersen
- 申请人地址： DK Copenhagen S
- 专利权人： Statens Serum Institut
- 当前专利权人： Statens Serum Institut
- 当前专利权人地址： DK Copenhagen S
- 代理机构： Knobbe Martens Olson & Bear LLP
- 优先权： DK200500924 20050623; DK200501393 20051005
- 主分类号： A61K39/04
- IPC分类号： A61K39/04 ; A61K39/02 ; C07H21/04
摘要：
The invention is related to an immunogenic composition, vaccine or pharmaceutical composition for preventing, boosting or treating infection caused by a species of the tuberculosis complex (M. tuberculosis, M. Bovis, M. africanum, M. microti). The immunogenic composition, vaccine or pharmaceutical composition comprise a fusion polypeptide, which comprises one or more starvation antigens from M. tuberculosis, the units of the fusion polypeptide being M. tuberculosis antigens. Further, the invention is related to the use of a vaccine comprising a fusion polypeptide sequence or nucleic acid sequence of the invention given at the same time as BCG, either mixed with BCG or administered separately at different sites or routes for preparing said immunogenic composition, vaccine, or pharmaceutical composition.
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