发明授权
- 专利标题: Apparatus and method of using porous material for antigen separation, identification, and quantification with electrophoresis techniques
- 专利标题(中): 使用多孔材料进行抗原分离,鉴定和电泳技术定量的装置和方法
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申请号: US12123714申请日: 2008-05-20
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公开(公告)号: US08105844B2公开(公告)日: 2012-01-31
- 发明人: Zhen Hong Sun , Tao Pan , Wendy Wang , Xuanbin Liu
- 申请人: Zhen Hong Sun , Tao Pan , Wendy Wang , Xuanbin Liu
- 申请人地址: US NJ Morristown
- 专利权人: Honeywell International Inc.
- 当前专利权人: Honeywell International Inc.
- 当前专利权人地址: US NJ Morristown
- 代理机构: Munck Carter, LLP
- 主分类号: G01N33/563
- IPC分类号: G01N33/563
摘要:
An apparatus includes a porous membrane for retaining antigens from a sample as the sample passes through the membrane. The apparatus also includes a first binding region within the membrane. The first binding region includes antibodies associated with a first antigen of interest. At least some of the antigens retained in the membrane are brought into contact with the first binding region by applying an electrophoresis field across the membrane. The porous membrane could also include an electrophoresis buffer. A presence of the first antigen of interest could be detected by exposing the first binding region to a chemiluminescent reagent, and a quantity of the first antigen of interest could be determined by performing a chemiluminescent assay on the binding region.