发明授权
- 专利标题： Renin inhibitors
- 专利标题（中）： 肾素抑制剂
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申请号： US12665219申请日： 2008-06-20
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公开(公告)号： US08106221B2公开(公告)日： 2012-01-31
- 发明人: John J. Baldwin , Salvacion Cacatian , David A. Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Alexey V. Ishchenko , Lanqi Jia , Gerard McGeehan , Robert D. Simpson , Suresh B. Singh , Colin M. Tice , Zhenrong Xu , Jing Yuan , Wei Zhao , Linghang Zhuang
- 申请人： John J. Baldwin , Salvacion Cacatian , David A. Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Alexey V. Ishchenko , Lanqi Jia , Gerard McGeehan , Robert D. Simpson , Suresh B. Singh , Colin M. Tice , Zhenrong Xu , Jing Yuan , Wei Zhao , Linghang Zhuang
- 申请人地址： US PA Fort Washington
- 专利权人： Vitae Pharmaceuticals, Inc.
- 当前专利权人： Vitae Pharmaceuticals, Inc.
- 当前专利权人地址： US PA Fort Washington
- 代理机构： Hamilton, Brook, Smith & Reynolds, P.C.
- 国际申请： PCT/US2008/007661 WO 20080620
- 国际公布： WO2008/156816 WO 20081224
- 主分类号： C07D325/00
- IPC分类号： C07D325/00 ; C07D315/00 ; C07D493/00 ; C07C275/04 ; A61K31/351 ; A61K31/17 ; A01N47/28
摘要：
The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.
公开/授权文献
- US20100144825A1 Renin Inhibitors 公开/授权日：2010-06-10
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