发明授权
- 专利标题: Anti-IL-17 antibodies
- 专利标题(中): 抗IL-17抗体
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申请号: US12908892申请日: 2010-10-21
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公开(公告)号: US08110191B2公开(公告)日: 2012-02-07
- 发明人: Barrett Allan , Chi-Kin Chow , Ling Liu , Jirong Lu , Jonathan Wendell Tetreault , Ying Tang
- 申请人: Barrett Allan , Chi-Kin Chow , Ling Liu , Jirong Lu , Jonathan Wendell Tetreault , Ying Tang
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 代理商 Gregory A. Cox
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/24
摘要:
Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.
公开/授权文献
- US20110027290A1 ANTI-IL-17 ANTIBODIES 公开/授权日:2011-02-03
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