发明授权
- 专利标题： Compositions and methods for treatment of cervical cancer
- 专利标题（中）： 用于治疗子宫颈癌的组合物和方法
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申请号： US11715497申请日： 2007-03-08
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公开(公告)号： US08114414B2公开(公告)日： 2012-02-14
- 发明人: Yvonne Paterson , John Rothman
- 申请人： Yvonne Paterson , John Rothman
- 申请人地址： US PA Philadelphia
- 专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Pearl Cohen Zedek Latzer, LLP
- 代理商 Mark S. Cohen
- 主分类号： A61K39/02
- IPC分类号： A61K39/02
摘要：
The present invention provides methods of treating, protecting against, and inducing an immune response against cervical cancer, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO fragment and an E7 and/or E6 antigen. The present invention also provides methods for inducing an anti-E7 response in a human subject and treating HPV-mediated diseases, disorders, and symptoms comprising administration of the recombinant Listeria strain.
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