发明授权
US08114878B2 6,7-dihydrothieno[3,2-d]pyrimidine for the treatment of inflammatory diseases
有权
6,7-二氢噻吩并[3,2-d]嘧啶,用于治疗炎性疾病
- 专利标题: 6,7-dihydrothieno[3,2-d]pyrimidine for the treatment of inflammatory diseases
- 专利标题(中): 6,7-二氢噻吩并[3,2-d]嘧啶,用于治疗炎性疾病
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申请号: US11736703申请日: 2007-04-18
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公开(公告)号: US08114878B2公开(公告)日: 2012-02-14
- 发明人: Pascale Pouzet , Christoph Hoenke , Rolf Goeggel , Birgit Jung , Peter Nickolaus , Dennis Fiegen , Thomas Fox
- 申请人: Pascale Pouzet , Christoph Hoenke , Rolf Goeggel , Birgit Jung , Peter Nickolaus , Dennis Fiegen , Thomas Fox
- 申请人地址: DE Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim am Rhein
- 代理商 Michael P. Morris; Timothy X. Witkowski
- 优先权: EP06112779 20060419
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; A61K31/519 ; A61K31/497 ; A61P37/06
摘要:
The invention relates to new dihydrothienopyrimidine of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein X is SO or SO2, but preferably SO, and wherein R1, R2 and R3 have the meanings given in the description, and which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.