A cartridge gun is provided. The cartridge gun comprises a cartridge holder, a plurality of resilient gripping elements, a displaceable piston rod for moving a piston in a cartridge, and an actuating device for displacing the piston rod. The cartridge holder comprises a cylindrical base for receiving the floor region of the cartridge in which the gripping elements project radially outwardly from the center of the cartridge holder in the direction towards the housing into an annular groove of the base up to the outside wall of the annular groove in the base and are held in the center of the base by means of a hub. Means are further arranged at the front end of the piston rod which are designated to press the ends of the resilient gripping elements in the direction towards the housing when the piston rod is fully retracted, allowing the removal of the cartridge from the cartridge gun.