发明授权
- 专利标题: Recombinant microorganisms for increased production of organic acids
- 专利标题(中): 用于增加有机酸生产的重组微生物
-
申请号: US11722579申请日: 2005-12-16
-
公开(公告)号: US08119377B2公开(公告)日: 2012-02-21
- 发明人: Jian Yi , Susanne Kleff , Michael V. Guettler
- 申请人: Jian Yi , Susanne Kleff , Michael V. Guettler
- 申请人地址: US MI Lansing
- 专利权人: Michigan Biotechnology Institute
- 当前专利权人: Michigan Biotechnology Institute
- 当前专利权人地址: US MI Lansing
- 代理机构: Dickinson Wright PLLC
- 国际申请: PCT/US2005/045714 WO 20051216
- 国际公布: WO2006/083410 WO 20060810
- 主分类号: C12N1/20
- IPC分类号: C12N1/20 ; C12N15/74
摘要:
Disclosed are recombinant microorganisms for producing organic acids. The recombinant microorganisms express a polypeptide that has the enzymatic activity of an enzyme that is utilized in the pentose phosphate cycle. The recombinant microorganism may include recombinant Actinobacillus succinogenes that has been transformed to express a Zwischenferment (Zwf) gene. The recombinant microorganisms may be useful in fermentation processes for producing organic acids such as succinic acid and lactic acid. Also disclosed are novel plasmids that are useful for transforming microorganisms to produce recombinant microorganisms that express enzymes such as Zwf.
公开/授权文献
信息查询
IPC分类: