Invention Grant
- Patent Title: Double-stranded nucleic acid molecule cancer cell proliferation inhibitor and pharmaceutical agent suitable for prevention or treatment of uterine cancer, breast cancer, and bladder cancer
- Patent Title (中): 双链核酸分子癌细胞增殖抑制剂和适用于预防或治疗子宫癌,乳腺癌和膀胱癌的药剂
-
Application No.: US12642979Application Date: 2009-12-21
-
Publication No.: US08124754B2Publication Date: 2012-02-28
- Inventor: Satoshi Inoue , Kazuhiro Ikeda
- Applicant: Satoshi Inoue , Kazuhiro Ikeda
- Applicant Address: JP Saitama JP Tokyo
- Assignee: Saitama Medical University,RNAI Co., Ltd.
- Current Assignee: Saitama Medical University,RNAI Co., Ltd.
- Current Assignee Address: JP Saitama JP Tokyo
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: JP2007-162641 20070620
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/11

Abstract:
A double-stranded nucleic acid molecule for suppressing the expression of at least one of COX7RP and Efp genes which includes (a) a sense strand which includes a nucleotide sequence corresponding to a target sequence indicated by any one of SEQ ID Nos.: 1 to 38 and (b) an antisense strand which includes a nucleotide sequence complementary to that of the sense strand specified in (a); a cancer cell proliferation inhibitor with the double-stranded nucleic acid molecule and against at least one of uterine, breast and bladder cancer cells; and a pharmaceutical agent with the cancer cell proliferation inhibitor and against at least one of uterine, breast and bladder cancers.
Public/Granted literature
Information query