发明授权
US08129371B2 Thienopyrimidine and pyrazolopyrimidine compounds and their use as mTOR kinase and PI3 kinase inhibitors
失效
噻吩并嘧啶和吡唑并嘧啶化合物及其作为mTOR激酶和PI3激酶抑制剂的用途
- 专利标题： Thienopyrimidine and pyrazolopyrimidine compounds and their use as mTOR kinase and PI3 kinase inhibitors
- 专利标题（中）： 噻吩并嘧啶和吡唑并嘧啶化合物及其作为mTOR激酶和PI3激酶抑制剂的用途
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申请号： US12251712申请日： 2008-10-15
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公开(公告)号： US08129371B2公开(公告)日： 2012-03-06
- 发明人: Arie Zask , Joshua Aaron Kaplan , Jeroen Cunera Verheijen , Kevin J. Curran , David James Richard , Semiramis Ayral-Kaloustian
- 申请人： Arie Zask , Joshua Aaron Kaplan , Jeroen Cunera Verheijen , Kevin J. Curran , David James Richard , Semiramis Ayral-Kaloustian
- 申请人地址： US NJ Madison
- 专利权人： Wyeth LLC
- 当前专利权人： Wyeth LLC
- 当前专利权人地址： US NJ Madison
- 代理商 David A. Rubin
- 主分类号： C07D265/36
- IPC分类号： C07D265/36 ; C07D265/28 ; A61K31/537 ; A61P37/06 ; A61P35/00 ; C07D487/04 ; C07D495/04
摘要：
The invention relates to thienopyrimidine and pyrazolopyrimidine compounds of the Formulas (Ia) and (IIa), or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein compositions comprising the compounds, and methods for making and using the compounds.
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