发明授权
US08129390B2 Carboxamide, sulfonamide and amine compounds and methods for using the same
有权
甲酰胺，磺酰胺和胺化合物及其使用方法
- 专利标题： Carboxamide, sulfonamide and amine compounds and methods for using the same
- 专利标题（中）： 甲酰胺，磺酰胺和胺化合物及其使用方法
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申请号： US12334201申请日： 2008-12-12
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公开(公告)号： US08129390B2公开(公告)日： 2012-03-06
- 发明人: Ihab S. Darwish , Jiaxin Yu , Hui Hong , Rajinder Singh , Sambaiah Thota , Xiang Xu
- 申请人： Ihab S. Darwish , Jiaxin Yu , Hui Hong , Rajinder Singh , Sambaiah Thota , Xiang Xu
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 代理商 Travis Young
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/44 ; C07D403/00 ; C07D491/12
摘要：
Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R4, D, E, J, T, p, q and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
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