发明授权
US08133876B2 Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
有权
用于调节小非编码RNA的低聚化合物和组合物
- 专利标题： Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
- 专利标题（中）： 用于调节小非编码RNA的低聚化合物和组合物
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申请号： US12345891申请日： 2008-12-30
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公开(公告)号： US08133876B2公开(公告)日： 2012-03-13
- 发明人: C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Eric G. Marcusson
- 申请人： C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Eric G. Marcusson
- 申请人地址： US CA Carlsbad
- 专利权人： Regulus Therapeutics Inc.
- 当前专利权人： Regulus Therapeutics Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Casimir Jones, S.C.
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07H21/04
摘要：
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.
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