Invention Grant
US08134029B2 Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine
有权
用反式4-（3,4-二氯苯基）-1,2,3,4-四氢-1-萘胺处理CNS病症
- Patent Title: Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine
- Patent Title (中): 用反式4-（3,4-二氯苯基）-1,2,3,4-四氢-1-萘胺处理CNS病症
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Application No.: US12847270Application Date: 2010-07-30
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Publication No.: US08134029B2Publication Date: 2012-03-13
- Inventor: Thomas Jerussi , Qun Kevin Fang , Mark G. Currie
- Applicant: Thomas Jerussi , Qun Kevin Fang , Mark G. Currie
- Applicant Address: US MA Marlborough
- Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee Address: US MA Marlborough
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- Main IPC: C07C211/45
- IPC: C07C211/45 ; C07C211/42 ; C07C233/15 ; A61K31/135 ; A61K31/03 ; A61K31/165
Abstract:
Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
Public/Granted literature
- US20100292340A1 Treatment of CNS Disorders With trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine Public/Granted day:2010-11-18
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