发明授权
- 专利标题: Methods for treating lung cancers
- 专利标题(中): 肺癌治疗方法
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申请号: US12278763申请日: 2006-02-10
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公开(公告)号: US08138167B2公开(公告)日: 2012-03-20
- 发明人: Yusuke Nakamura , Yataro Daigo
- 申请人: Yusuke Nakamura , Yataro Daigo
- 申请人地址: JP Kanagawa
- 专利权人: Oncotherapy Science, Inc.
- 当前专利权人: Oncotherapy Science, Inc.
- 当前专利权人地址: JP Kanagawa
- 代理机构: Kilpatrick Townsend & Stockton LLP
- 国际申请: PCT/JP2006/302345 WO 20060210
- 国际公布: WO2007/091328 WO 20070816
- 主分类号: A01N43/00
- IPC分类号: A01N43/00
摘要:
The present invention provided methods for treating lung cancers using therapeutic agents for lung cancers comprising erbB receptor inhibitors as active ingredients. Methods for examining the responsiveness of lung cancer patients to erbB receptor inhibitors by using blood amphiregulin (AREG) as an indicator were provided. Furthermore, methods for treating lung cancers in which responsiveness to an erbB receptor inhibitor is determined based on blood AREG concentration, and in which therapeutic agents are selectively administered to patients expected to be responsive, were also provided. Advanced therapeutic effects can be expected by administering an erbB receptor inhibitor to patients predicted to be responsive. The present invention contributes to the improvement of therapeutic effects of gefitinib (Product name: Iressa®) and such on lung cancers.
公开/授权文献
- US20090186892A1 METHODS FOR TREATING LUNG CANCERS 公开/授权日:2009-07-23
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