发明授权
- 专利标题： Modulation of apolipoprotein (A) expression
- 专利标题（中）： 载脂蛋白（A）表达的调节
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申请号： US12765647申请日： 2010-04-22
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公开(公告)号： US08138328B2公开(公告)日： 2012-03-20
- 发明人: Rosanne M. Crooke , Mark J. Graham
- 申请人： Rosanne M. Crooke , Mark J. Graham
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Isis Pharmaceuticals, Inc. Patent Dept. Jones Day
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07H21/02 ; A61K48/00
摘要：
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein(a). The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein(a). Methods of using these compounds for modulation of apolipoprotein(a) expression and for diagnosis and treatment of disease associated with expression of apolipoprotein(a) are provided.
公开/授权文献
- US20100273860A1 MODULATION OF APOLIPOPROTEIN (a) EXPRESSION 公开/授权日：2010-10-28
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