A space domain filter detecting method in a multi-antennas wireless communication system, which processes time and space domain interference differently. The space domain filter detecting method comprises the following steps: firstly, the received signals are matched-combined in time domain and space domain; secondly, using the combined signals as an observation value, the space domain filtering is performed; thirdly, an estimated value is subtracted from the filtered signals, and the result is taken as a detection output, which is sent to a determiner in a non-error control coding system to get a hard determination output or is sent to a determiner in an error control coding system to get a soft determination output that is finally sent to a coder. The method promotes the transmission rate and the anti-interference ability and advances the spectrum efficiency.