The present disclosure describes a method and apparatus for transmit power calibration in a frequency division multiplexed wireless system (100). The method may include receiving (320), at a user equipment (120), a signal from a base station (130) in a frequency division multiplexed wireless system and mapping (330), in response to receiving the signal from the base station, a power control calibration region to an uplink symbol in a subframe to establish a mapped uplink symbol using predetermined criteria. The method can also include calibrating (350) a transmit power based on transmission in the calibration region and transmitting (360) data at the calibrated transmit power on at least one other symbol following the mapped uplink symbol.