Invention Grant
- Patent Title: Kinase inhibitors
- Patent Title (中): 激酶抑制剂
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Application No.: US12513928Application Date: 2007-11-07
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Publication No.: US08148361B2Publication Date: 2012-04-03
- Inventor: Rajeev S. Bhide , Anne Marinier
- Applicant: Rajeev S. Bhide , Anne Marinier
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliot Korsen
- International Application: PCT/US2007/083850 WO 20071107
- International Announcement: WO2008/060907 WO 20080522
- Main IPC: A61K31/437
- IPC: A61K31/437 ; A61K31/397 ; C07D471/04 ; A61P35/00 ; A61P7/00
Abstract:
The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts thereof. The Formula (I) compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1 and IGFR-1, thereby making them useful as anti-cancer agents. The formula (I) compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Public/Granted literature
- US20100041636A1 NOVEL KINASE INHIBITORS Public/Granted day:2010-02-18
Information query
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