发明授权
US08148385B2 Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists
有权
取代的[1,2,3]三唑并[4,5-d]嘧啶衍生物作为ADP P2Y12受体拮抗剂
- 专利标题: Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists
- 专利标题(中): 取代的[1,2,3]三唑并[4,5-d]嘧啶衍生物作为ADP P2Y12受体拮抗剂
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申请号: US11980907申请日: 2007-10-31
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公开(公告)号: US08148385B2公开(公告)日: 2012-04-03
- 发明人: Han-Cheng Zhang , Bruce E. Maryanoff , Hong Ye , Cailin Chen
- 申请人: Han-Cheng Zhang , Bruce E. Maryanoff , Hong Ye , Cailin Chen
- 申请人地址: BE
- 专利权人: Janssen Pharmaceutica N.V.
- 当前专利权人: Janssen Pharmaceutica N.V.
- 当前专利权人地址: BE
- 代理商 Yuriy P. Stercho
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/519 ; A61P7/02 ; A61P9/10 ; A61P37/06 ; A61P25/06
摘要:
The present invention is directed to novel bicyclic triazolopyrimidine compounds of Formula (I) or a form thereof: wherein X1, X2, R1, R2, R3 and R4 are as defined herein, and their methods of preparation and use as ADP inhibitors.
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