发明授权
US08148429B2 Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands
有权
使用亚苄氨基鸟嘌呤和羟基胍来作为黑皮质素受体配体
- 专利标题： Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands
- 专利标题（中）： 使用亚苄氨基鸟嘌呤和羟基胍来作为黑皮质素受体配体
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申请号： US11639190申请日： 2006-12-15
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公开(公告)号： US08148429B2公开(公告)日： 2012-04-03
- 发明人: Torbjörn Lundstedt , Anna Skottner , Elisabeth Seifert
- 申请人： Torbjörn Lundstedt , Anna Skottner , Elisabeth Seifert
- 申请人地址： SE
- 专利权人： AnaMar AB
- 当前专利权人： AnaMar AB
- 当前专利权人地址： SE
- 代理机构： Bacon & Thomas, PLLC
- 优先权： GB0019357.3 20000807
- 主分类号： A61K31/155
- IPC分类号： A61K31/155 ; A01N37/52 ; A01N37/30
摘要：
The present invention relates to the use of compounds of general formula (I) as ligands to the melanocortin receptors and/or for treatment of disorders in the melanocortin system: wherein X is H or OH; R1, R2, R3, R4 and R5 are the same or different and are selected from hydrogen, halogen, alkyl having 1 to 5 carbon atoms, electron donor groups such as alkoxy having 1-5 carbon atoms or hydroxy, electron acceptor groups selected from cyano, nitro, trifluoroalkyl or amide; alkylamino, benzoyloxy, nitroxy, phenyl or sulpho; and the pharmacologically active salts thereof.
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