Invention Grant
- Patent Title: Detecting and handling coincidence in particle analysis
- Patent Title (中): 在粒子分析中检测和处理巧合
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Application No.: US12249473Application Date: 2008-10-10
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Publication No.: US08154273B2Publication Date: 2012-04-10
- Inventor: Ted W. Britton , Jiuliu Lu , Jeffrey L. Rose
- Applicant: Ted W. Britton , Jiuliu Lu , Jeffrey L. Rose
- Applicant Address: US CA Brea
- Assignee: Beckman Coulter, Inc.
- Current Assignee: Beckman Coulter, Inc.
- Current Assignee Address: US CA Brea
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Andrew L. Reibman
- Main IPC: G01N27/00
- IPC: G01N27/00

Abstract:
Methods and systems substantially eliminate data representative of coincident events from particle analyzer data. A fluid sample containing particles for analysis is prepared. Using an electrical or optical measurement device, signals are sensed. Each signal corresponds to events detected in a sub-sample of the fluid sample flowing through a measurement region in the particle analyzer. The existence of coincidence in the events is determined based on measuring a peak and first and second points of each of the signals. The first and second points have a signal value corresponding to a predetermined portion of the peak. Results data based upon the coincident events and non-coincident events is generated. The results data is then analyzed. In various examples, the method is applicable to a variety of particle types, and may be implemented on different types of particle analyzers including hematology analyzer and flow cytometers.
Public/Granted literature
- US20100090677A1 Detecting and Handling Coincidence in Particle Analysis Public/Granted day:2010-04-15
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