发明授权
- 专利标题: Azacytidine analogues and uses thereof
- 专利标题(中): 氮杂胞苷类似物及其用途
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申请号: US12238125申请日: 2008-09-25
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公开(公告)号: US08158605B2公开(公告)日: 2012-04-17
- 发明人: Lewis Silverman , James Holland
- 申请人: Lewis Silverman , James Holland
- 申请人地址: US NY New York
- 专利权人: Mount Sinai School of Medicine
- 当前专利权人: Mount Sinai School of Medicine
- 当前专利权人地址: US NY New York
- 代理机构: LeClairRyan, a Professional Corporation
- 主分类号: A01N43/04
- IPC分类号: A01N43/04 ; A61K31/70
摘要:
The present invention is directed toward compounds of Formula (I) as follows: wherein, R is H, R5C(O); R1 is where the crossing dashed line illustrates the bond formed joining R1 to the molecule of Formula (I); R2 and R3 are independently OH or H, provided that R2 and R3 are not simultaneously OH; R4 is H or R5C(O), provided that R and R4 are not simultaneously H; and R5 is a C3-C26 alkenyl, or a pharmaceutical salt thereof. Methods of making and using these compounds are also disclosed.
公开/授权文献
- US20090209482A1 AZACYTIDINE ANALOGUES AND USES THEREOF 公开/授权日:2009-08-20
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