Invention Grant
US08158656B2 2-indolinone derivatives as multi-target protein kinase inhibitors and histone deacetylase inhibitors
有权
2-二氢吲哚酮衍生物作为多靶蛋白激酶抑制剂和组蛋白脱乙酰酶抑制剂
- Patent Title: 2-indolinone derivatives as multi-target protein kinase inhibitors and histone deacetylase inhibitors
- Patent Title (中): 2-二氢吲哚酮衍生物作为多靶蛋白激酶抑制剂和组蛋白脱乙酰酶抑制剂
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Application No.: US12463107Application Date: 2009-05-08
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Publication No.: US08158656B2Publication Date: 2012-04-17
- Inventor: Xian-Ping Lu , Zhi-Bin Li , Zhi-Qiang Ning
- Applicant: Xian-Ping Lu , Zhi-Bin Li , Zhi-Qiang Ning
- Applicant Address: CN Shenzhen
- Assignee: Shenzhen Chipscreen Biosciences Ltd.
- Current Assignee: Shenzhen Chipscreen Biosciences Ltd.
- Current Assignee Address: CN Shenzhen
- Agency: Eckert Seamans Cherin & Mellott, LLC
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D401/14
Abstract:
The present invention relates to 2-indolinone derivatives which are capable of inhibiting protein kinases and histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal protein kinase activities or abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.
Public/Granted literature
- US20090298886A1 2-INDOLINONE DERIVATIVES AS MULTI-TARGET PROTEIN KINASE INHIBITORS AND HISTONE DEACETYLASE INHIBITORS Public/Granted day:2009-12-03
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