Invention Grant
- Patent Title: Process for the preparation of Rho-kinase inhibitor compounds
- Patent Title (中): 制备Rho激酶抑制剂化合物的方法
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Application No.: US12470377Application Date: 2009-05-21
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Publication No.: US08158796B2Publication Date: 2012-04-17
- Inventor: Jin She , Jonathan Bryan deCamp , Paul S. Watson , David J. Slade
- Applicant: Jin She , Jonathan Bryan deCamp , Paul S. Watson , David J. Slade
- Applicant Address: US NJ Whitehouse Station
- Assignee: Inspire Pharmaceuticals, Inc.
- Current Assignee: Inspire Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Whitehouse Station
- Agency: Perkins Coie LLP.
- Agent Viola T. Kung
- Main IPC: C07D217/22
- IPC: C07D217/22
Abstract:
The present invention is directed to practical high-yielding synthetic processes to prepare compounds of general Formula III, IV, V, VII, VIII, IX, X, XII, XIV, and XV. Such compounds are useful as final products or can be used as intermediates and be further modified to prepare other desired products such as rho-kinase inhibitors. The present invention is also directed to certain novel compounds and/or novel solid forms of certain compounds.
Public/Granted literature
- US20100022775A1 PROCESS FOR THE PREPARATION OF RHO-KINASE INHIBITOR COMPOUNDS Public/Granted day:2010-01-28
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