发明授权
- 专利标题： Process for the preparation of Rho-kinase inhibitor compounds
- 专利标题（中）： 制备Rho激酶抑制剂化合物的方法
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申请号： US12470377申请日： 2009-05-21
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公开(公告)号： US08158796B2公开(公告)日： 2012-04-17
- 发明人: Jin She , Jonathan Bryan deCamp , Paul S. Watson , David J. Slade
- 申请人： Jin She , Jonathan Bryan deCamp , Paul S. Watson , David J. Slade
- 申请人地址： US NJ Whitehouse Station
- 专利权人： Inspire Pharmaceuticals, Inc.
- 当前专利权人： Inspire Pharmaceuticals, Inc.
- 当前专利权人地址： US NJ Whitehouse Station
- 代理机构： Perkins Coie LLP.
- 代理商 Viola T. Kung
- 主分类号： C07D217/22
- IPC分类号： C07D217/22
摘要：
The present invention is directed to practical high-yielding synthetic processes to prepare compounds of general Formula III, IV, V, VII, VIII, IX, X, XII, XIV, and XV. Such compounds are useful as final products or can be used as intermediates and be further modified to prepare other desired products such as rho-kinase inhibitors. The present invention is also directed to certain novel compounds and/or novel solid forms of certain compounds.
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