Techniques for performing equalization at a receiver are described. In an aspect, equalization is performed by sub-sampling an over-sampled input signal to obtain multiple sub-sampled signals. An over-sampled channel impulse response estimate is derived and sub-sampled to obtain multiple sub-sampled channel impulse response estimates. At least one set of equalizer coefficients is derived based on at least one sub-sampled channel impulse response estimate. At least one sub-sampled signal is filtered with the at least one set of equalizer coefficients to obtain at least one output signal. One sub-sampled signal (e.g., with largest energy) may be selected and equalized based on a set of equalizer coefficients derived from an associated sub-sampled channel impulse response estimate. Alternatively, the multiple sub-sampled signals may be equalized based on multiple sets of equalizer coefficients, which may be derived separately or jointly. The equalizer coefficients may be derived in the time domain or frequency domain.