The present invention provides method and system for data communication in the human body and a sensor therefor. The method and system transmit information through the human body to a receiver located outside the human body using low current and voltage polarity, so that they cause no damage to the human body and achieve low power consumption and better receiving sensitivity. In addition, the sensor contains a CMOS image sensor on which all circuits are integrated without radio transmitter and antenna, so that it achieves a low-priced and small-sized capsule type endoscope.