A technique for performing data prefetching using indirect addressing includes determining a first memory address of a pointer associated with a data prefetch instruction. Content, that is included in a first data block (e.g., a first cache line) of a memory, at the first memory address is then fetched. An offset is then added to the content of the memory at the first memory address to provide a first offset memory address. A second memory address is then determined based on the first offset memory address. A second data block (e.g., a second cache line) that includes data at the second memory address is then fetched (e.g., from the memory or another memory). A data prefetch instruction may be indicated by a unique operational code (opcode), a unique extended opcode, or a field (including one or more bits) in an instruction.