A slide assembly having an adjustment mechanism includes an inner rail, an adjusting lever, and a guide block. The inner rail includes a first slot, a pivoting portion, and a second slot thereon. The adjusting lever includes a first hole, a middle section pivoted to the inner rail, and a second hole. The first hole corresponds in position to the first slot, and the second hole corresponds in position to the second slot. The guide block is pivoted to the second hole of the adjusting lever. A protruding portion is eccentrically disposed on the guide block. The protruding portion is moved to lean against a portion of the second slot by turning the guide block. The adjusting lever deflects and the first hole slides in relation to the first slot. A fastening member penetrates through the first hole to connect a drawer or similar object so that the drawer can be tuned fine for a higher or lower position.