Invention Grant
US08163750B2 Fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone HSP 90
有权
芴衍生物，含有该衍生物的组合物及其作为蛋白质分子伴侣HSP90抑制剂的用途
- Patent Title: Fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone HSP 90
- Patent Title (中): 芴衍生物，含有该衍生物的组合物及其作为蛋白质分子伴侣HSP90抑制剂的用途
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Application No.: US12625005Application Date: 2009-11-24
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Publication No.: US08163750B2Publication Date: 2012-04-24
- Inventor: Fabienne Thompson , Patrick Mailliet , Jean-Marie Ruxer , Helene Goulaouic , Francois Vallee , Herve Minoux , Fabienne Pilorge , Luc Bertin , Stephane Hourcade , Maria Mendez-Perez , Peter Hamley
- Applicant: Fabienne Thompson , Patrick Mailliet , Jean-Marie Ruxer , Helene Goulaouic , Francois Vallee , Herve Minoux , Fabienne Pilorge , Luc Bertin , Stephane Hourcade , Maria Mendez-Perez , Peter Hamley
- Applicant Address: FR Paris
- Assignee: Sanofi-Aventis
- Current Assignee: Sanofi-Aventis
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser PC
- Priority: FR0609331 20061024
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437
Abstract:
The present invention relates to compounds of formula (I): wherein R1, R2, R2′, L, Het, p and p′ are as defined herein, compositions containing them, and their use as medicinal products.
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