Invention Grant
- Patent Title: Process for producing laurolactam
- Patent Title (中): 生产月桂内酰胺的方法
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Application No.: US12526494Application Date: 2008-02-08
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Publication No.: US08163899B2Publication Date: 2012-04-24
- Inventor: Kazuaki Ishihara , Junichi Kugimoto , Joji Kawai
- Applicant: Kazuaki Ishihara , Junichi Kugimoto , Joji Kawai
- Applicant Address: JP Nagoya-shi JP Ube-shi
- Assignee: National University Corporation Nagoya University,UBE Industries, Ltd.
- Current Assignee: National University Corporation Nagoya University,UBE Industries, Ltd.
- Current Assignee Address: JP Nagoya-shi JP Ube-shi
- Agency: Knobbe Martens Olson & Bear LLP
- Priority: JP2007-030474 20070209
- International Application: PCT/JP2008/052192 WO 20080208
- International Announcement: WO2008/096873 WO 20080814
- Main IPC: C07D201/04
- IPC: C07D201/04

Abstract:
Disclosed is a method for producing laurolactam from cyclododecanone and hydroxylamine in a simple process and with high efficiency. The method comprises the following steps (a) to (e): (a) reacting cyclododecanone with hydroxylamine in an aqueous solution in the presence of an excess amount of cyclododecanone or a solvent to produce cyclododecanone oxime; (b) separating the reaction mixture obtained after the oxime-forming step into an oil and an aqueous phases and collecting a solution of cyclododecanone oxime of the oil phase as; (c) removing dissolved water from the solution of cyclododecanone oxime which is collected as an oily phase in the oil/aqueous phase separation step; (d) producing laurolactam from cyclododecanone oxime by rearrangement reaction using an aromatic-ring containing compound as a rearrangement catalyst; and (e) separating the produced laurolactam from the reaction mixture after the rearrangement step and purifying the laurolactam.
Public/Granted literature
- US20100324283A1 PROCESS FOR PRODUCING LAUROLACTAM Public/Granted day:2010-12-23
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