发明授权
US08163927B2 Azabicyclo [3.1.0] hexane derivatives as modulators of dopamine D3 receptors
失效
氮杂二环[3.1.0]己烷衍生物作为多巴胺D3受体的调节剂
- 专利标题: Azabicyclo [3.1.0] hexane derivatives as modulators of dopamine D3 receptors
- 专利标题(中): 氮杂二环[3.1.0]己烷衍生物作为多巴胺D3受体的调节剂
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申请号: US12295024申请日: 2007-03-30
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公开(公告)号: US08163927B2公开(公告)日: 2012-04-24
- 发明人: Barbara Bertani , Fabrizio Micheli , Alessandra Pasquarello , Silvia Terreni
- 申请人: Barbara Bertani , Fabrizio Micheli , Alessandra Pasquarello , Silvia Terreni
- 申请人地址: GB Greenford, Middlesex
- 专利权人: Glaxo Group Limited
- 当前专利权人: Glaxo Group Limited
- 当前专利权人地址: GB Greenford, Middlesex
- 代理商 Bonnie L. Deppenbrock
- 优先权: GB0607896.8 20060403; GB0703387.1 20070221
- 国际申请: PCT/EP2007/053115 WO 20070330
- 国际公布: WO2007/113258 WO 20071011
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; A61K31/444
摘要:
The present invention relates to certain azabicyclic compounds of formula (I)′: wherein the several groups are defined herein and are modulators of dopamine D3 receptors, e.g. to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, or premature ejaculation.
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