Invention Grant
- Patent Title: Compositions and methods for topical delivery of oligonucleotides
- Patent Title (中): 用于局部递送寡核苷酸的组合物和方法
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Application No.: US11112451Application Date: 2005-04-21
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Publication No.: US08168600B2Publication Date: 2012-05-01
- Inventor: Sujatha Dokka , Scott Cooper , Susan Kelly , Gregory E. Hardee , James G. Karras
- Applicant: Sujatha Dokka , Scott Cooper , Susan Kelly , Gregory E. Hardee , James G. Karras
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K48/00
Abstract:
The present invention relates to compositions and methods which enhance the delivery of nucleic acids and other nucleosidic moieties via topical routes of administration. The invention relates to the use of an aqueous solution to preferentially deliver nucleic acids preferentially to hair follicles. The invention relates to a method of inhibiting hair growth comprising administration of a nucleic acid preferentially to a hair follicle.
Public/Granted literature
- US20050238606A1 Compositions and methods for topical delivery of oligonucleotides Public/Granted day:2005-10-27
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