Invention Grant
US08168639B2 Heterotricyclic compounds as serotonergic and/or dopaminergic agents and uses thereof
有权
异三环化合物作为血清素能和/或多巴胺能药物及其用途
- Patent Title: Heterotricyclic compounds as serotonergic and/or dopaminergic agents and uses thereof
- Patent Title (中): 异三环化合物作为血清素能和/或多巴胺能药物及其用途
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Application No.: US12532869Application Date: 2007-09-24
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Publication No.: US08168639B2Publication Date: 2012-05-01
- Inventor: Vladimir Kogan
- Applicant: Vladimir Kogan
- Applicant Address: LU Luxembourg
- Assignee: ATIR Holding S.A.
- Current Assignee: ATIR Holding S.A.
- Current Assignee Address: LU Luxembourg
- Priority: WOPCT/IL2007/000404 20070328
- International Application: PCT/IL2007/001174 WO 20070924
- International Announcement: WO2008/117269 WO 20081002
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/505 ; C07D401/00 ; C07D239/00 ; A01N43/54

Abstract:
Novel heterocyclic compounds of formula I: A-B-D Formula I or a pharmaceutically acceptable salt thereof, wherein: A is selected from the group consisting of a moiety having general Formula II and a moiety having general Formula III: B is a moiety selected from the group consisting of: D is a moiety selected from the group consisting of: which exhibit a dopamine receptor (preferably a D4 receptor) and/or a serotonine receptor (preferably 5HTA1 agonistic activity), processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of medical conditions associated with the dopaminergic and/or serotonergic systems (e.g., sexual disorders, dyskinesia, anxiety) are disclosed.
Public/Granted literature
- US20100216807A1 HETEROCYCLIC COMPOUNDS AS SEROTONERGIC AND / OR DOPAMINERGIC AGENTS AND USES THEREOF Public/Granted day:2010-08-26
Information query
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