发明授权
- 专利标题： Substituted carbinol compound
- 专利标题（中）： 取代甲醇化合物
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申请号： US12516944申请日： 2007-11-29
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公开(公告)号： US08168666B2公开(公告)日： 2012-05-01
- 发明人: Takayuki Matsuda , Ayumu Okuda , Minoru Koura , Yuki Yamaguchi , Sayaka Kurobuchi , Yuuichirou Watanabe , Kimiyuki Shibuya
- 申请人： Takayuki Matsuda , Ayumu Okuda , Minoru Koura , Yuki Yamaguchi , Sayaka Kurobuchi , Yuuichirou Watanabe , Kimiyuki Shibuya
- 申请人地址： JP Nagoya-shi
- 专利权人： Kowa Company, Ltd.
- 当前专利权人： Kowa Company, Ltd.
- 当前专利权人地址： JP Nagoya-shi
- 代理机构： Westerman, Hattori, Daniels & Adrian, LLP
- 优先权： JP2006-322963 20061130
- 国际申请： PCT/JP2007/001318 WO 20071129
- 国际公布： WO2008/065754 WO 20080605
- 主分类号： A61K31/4015
- IPC分类号： A61K31/4015 ; C07D233/32
摘要：
There is provided a novel LXRβ agonist useful as a preventative and/or therapeutic agent for arteriosclerosis; arteriosclerosis such as those resulting from diabetes; hyperlipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases caused by inflammatory cytokines, skin diseases such as allergic skin diseases, diabetes or Alzheimer's disease. The agonist is a carbinol derivative represented by the following general formula (1) or salt thereof, or their solvate.
公开/授权文献
- US20100063119A1 SUBSTITUTED CARBINOL COMPOUND 公开/授权日：2010-03-11
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