An image sensing device comprises a readout unit, an output amplifier, and a horizontal scanning unit, wherein the horizontal scanning unit scans a plurality of column signal holding circuits in a plurality of holding blocks in the readout unit in a direction along a row, in each holding block, a first operation in which the signal held in a first holding unit is transferred to a second holding unit via a transfer switch is performed, and subsequently, a second operation in which the signal held in the second holding unit is transferred to the output amplifier, and a third operation in which a signal output from a pixel is read out to the first holding unit are performed in parallel, and the second operation and the first operation are performed in parallel between different holding blocks in the plurality of holding blocks.