A technique is provided for installing a tubular hanger and tubular hanger seal in a wellhead. The technique comprises installing the tubular hanger with a setting tool. The tubular hanger may comprise a locking ring that is driven outward into engagement with a profile in the wellhead. The setting tool is adapted to rotate a moveable member of the tubular hanger relative to the tubular hanger body so as to drive the moveable member to expand the locking ring outward to engage a profile in the wellhead. The moveable member may be wedged between the locking ring and the tubular hanger body. The setting tool may be adapted to enable the moveable member and the tubular hanger body to be rotated independently. The annulus between the tubular hanger and the wellhead may be sealed by a seal that has a plurality of sealing elements that are coupled together by a series of catches.