Invention Grant
US08173665B2 I-pheny 1-3,4-dihydropyrimidin-2(1H)-one derivatives and their use
失效
1-苯基-1,3,4-二氢嘧啶-2（1H） - 酮衍生物及其用途
- Patent Title: I-pheny 1-3,4-dihydropyrimidin-2(1H)-one derivatives and their use
- Patent Title (中): 1-苯基-1,3,4-二氢嘧啶-2（1H） - 酮衍生物及其用途
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Application No.: US12509936Application Date: 2009-07-27
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Publication No.: US08173665B2Publication Date: 2012-05-08
- Inventor: Heike Gielen-Haertwig , Volkhart Min-Jian Li , Ulrich Rosentreter , Karl-Heinz Schlemmer , Swen Allerheiligen , Leila Telan , Lars Bärfacker , Jörg Keldenieh , Mary F. Fitzgerald , Kevin Nash , Barbara Albrecht , Dirk Meurer
- Applicant: Heike Gielen-Haertwig , Volkhart Min-Jian Li , Ulrich Rosentreter , Karl-Heinz Schlemmer , Swen Allerheiligen , Leila Telan , Lars Bärfacker , Jörg Keldenieh , Mary F. Fitzgerald , Kevin Nash , Barbara Albrecht , Dirk Meurer
- Applicant Address: DE Berlin
- Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee Address: DE Berlin
- Agent Karen B. King
- Priority: GB0220961.7 20020910; GB0311957.5 20030523
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505
Abstract:
The invention relates to 4-cyanophenyl, 2-sulfanyl, 1-phenyl pyrimidine derivatives, processes for their preparation, and pharmaceutical compositions of the same. Compounds and compositions of the invention are useful in the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction, and heart failure development.
Public/Granted literature
- US20100022537A1 I-PHENY 1-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE DERIVATIVES AND THEIR USE Public/Granted day:2010-01-28
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