Invention Grant
- Patent Title: Pyridine, pyrimidine and pyrazine derivatives as GPCR agonists
- Patent Title (中): 吡啶，嘧啶和吡嗪衍生物作为GPCR激动剂
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Application No.: US11794641Application Date: 2005-12-30
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Publication No.: US08173807B2Publication Date: 2012-05-08
- Inventor: Stuart Edward Bradley , Matthew Colin Thor Fyfe , Gerard Hugh Thomas
- Applicant: Stuart Edward Bradley , Matthew Colin Thor Fyfe , Gerard Hugh Thomas
- Applicant Address: GB Oxford
- Assignee: Prosidion Limited
- Current Assignee: Prosidion Limited
- Current Assignee Address: GB Oxford
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi; Heidi A. Erlacher
- Priority: GB0428514.4 20041231
- International Application: PCT/GB2005/050266 WO 20051230
- International Announcement: WO2006/070208 WO 20060706
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/4545 ; C07D401/14 ; A61P3/00 ; A61P3/04 ; A61P3/10
Abstract:
Compounds of formula (I): R1-A-V—B—R2, wherein V is phenyl or a 6-membered heteroaryl ring containing up to three N-atoms, or pharmaceutically acceptable salts thereof, are agonists of GPR116 and are useful for the treatment of obesity, and for the treatment of diabetes.
Public/Granted literature
- US20100035897A1 Pyridine, pyrimidine and pyrazine derivatives as gpcr agonists Public/Granted day:2010-02-11
Information query
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