发明授权
US08178310B2 Babesia microti genomic clones containing novel antigens useful in the diagnosis of Babesios
有权
含有可用于诊断巴西菌病的新型抗原的巴贝氏菌微基因组克隆
- 专利标题： Babesia microti genomic clones containing novel antigens useful in the diagnosis of Babesios
- 专利标题（中）： 含有可用于诊断巴西菌病的新型抗原的巴贝氏菌微基因组克隆
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申请号： US12386097申请日： 2009-04-14
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公开(公告)号： US08178310B2公开(公告)日： 2012-05-15
- 发明人: John G. Hoey , Hannah Venit , Martin E. Adelson , Eli Mordechai , Fernando Valois-Cruz
- 申请人： John G. Hoey , Hannah Venit , Martin E. Adelson , Eli Mordechai , Fernando Valois-Cruz
- 申请人地址： US NJ Hamilton
- 专利权人： Medical Diagnostic Laboratories, LLC
- 当前专利权人： Medical Diagnostic Laboratories, LLC
- 当前专利权人地址： US NJ Hamilton
- 代理商 Siu K. Lo, Esq.
- 主分类号： G01N33/569
- IPC分类号： G01N33/569 ; C07H21/04 ; C07K14/00 ; C12P21/06
摘要：
Disclosed are the cloning and expression of novel antigens in Babesia microti. The recombinant polypeptides are highly immunogenic. The polypeptides of the present invention provide the basis of a diagnostic assay that is sensitive, rapid and accurate using patient's sera. Also disclosed is an IgG and IgM ELISA using two novel recombinant antigens in the diagnosis of Babesia infection.