Invention Grant
US08178577B2 Tricyclic derivatives as potent and selective histone deacetylase inhibitors
有权
三环衍生物作为有效和选择性的组蛋白脱乙酰酶抑制剂
- Patent Title: Tricyclic derivatives as potent and selective histone deacetylase inhibitors
- Patent Title (中): 三环衍生物作为有效和选择性的组蛋白脱乙酰酶抑制剂
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Application No.: US12463176Application Date: 2009-05-08
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Publication No.: US08178577B2Publication Date: 2012-05-15
- Inventor: Xian-Ping Lu , Zhi-Bin Li , Zhi-Qiang Ning
- Applicant: Xian-Ping Lu , Zhi-Bin Li , Zhi-Qiang Ning
- Applicant Address: CN Shenzhen
- Assignee: Shenzhen Chipscreen Biosciences Ltd.
- Current Assignee: Shenzhen Chipscreen Biosciences Ltd.
- Current Assignee Address: CN Shenzhen
- Agency: Eckert Seamans Cherin & Mellott, LLC
- Main IPC: A61K31/382
- IPC: A61K31/382 ; A61K31/352 ; A61K31/16 ; C07D335/02 ; C07D311/82 ; C07C233/00
Abstract:
The present invention relates to certain tricyclic derivatives which are capable of inhibiting histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.
Public/Granted literature
- US20090292001A1 TRICYCLIC DERIVATIVES AS POTENT AND SELECTIVE HISTONE DEACETYLASE INHIBITORS Public/Granted day:2009-11-26
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